Eyeworld

I INNOVATIONS IN LENSES APRIL 2019 | EYEWORLD | 99 and astigmatism. Use of this approach requires both the LAL and a Light Delivery Device. "Many surgeons are eagerly awaiting the launch [of the Light Adjustable Lens]," said John Berdahl, MD. "There are post-approval studies that are underway. I am hopeful that the tech- nology is available in the next 12 to 18 months commercially." Dr. Chang was a clinical investiga- tor for the U.S. clinical trial and predicts that the technology will become available in the U.S. later this year. Although Nick Mamalis, MD, is now working with the Perfect Lens, he and colleague Liliana Werner, MD, PhD, performed the animal and lab studies for the LAL. "It's a very interesting tech- nology that can change the power of the lens im- plant," Dr. Mamalis said. However, it does require the use of a special IOL made by the company versus the use of a non-specific IOL, he said. Perfect Lens Dr. Mamalis and Dr. Werner now work with the Perfect Lens procedure, which uses a femtosec- ond laser to modify an implanted IOL. Surgeons can use the technology to correct spherical aber- ration, asphericity, toricity, and multifocality. Perfect Lens has created a femtosecond laser system for IOL power adjustment based on re- fractive index shaping. "Refractive index shaping combines a device, a mechanism, and a process," Dr. Chang said. "The device employs a femtosecond laser, an OCT, a scanner, and a proprietary objective lens. The mechanism is a laser material interaction that changes the refractive index of the targeted mate- rial. The processing is an algorithm that uses this mechanism to create a diffractive or refractive lens by modulating the laser energy and controlling the position of the refractive index change inside the IOL. Refractive index shaping is theoretically available for any hydrophilic or hydrophobic intra- ocular lens." The Perfect Lens technology also can be used several times and can reverse adjustments made previously, Dr. Werner said. The approach can create multifocality in a monofocal lens and turn Adjusting the power of the Light Adjustable Lens Source: John Berdahl, MD continued on page 100 About the doctors John Berdahl, MD Vance Thompson Vision Sioux Falls, South Dakota David F. Chang, MD Clinical professor, University of California, San Francisco Scott MacRae, MD Professor Flaum Eye Institute University of Rochester Rochester, New York Nick Mamalis, MD Professor and co-director Intermountain Ocular Research Center, John A. Moran Eye Center University of Utah Salt Lake City Liliana Werner, MD, PhD Professor and co-director, Intermountain Ocular Research Center, John A. Moran Eye Center University of Utah Salt Lake City Len Zheleznyak, PhD Vice president of vision science Clerio Vision West Henrietta, New York

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