EW FEATURE
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AT A GLANCE
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Reference
1. Kass MA, Heuer DK, Higginbotham EJ, et al.
The Ocular Hypertension Treatment Study: a
randomized trial determines that topical ocular
hypotensive medication delays or prevents the
onset of primary open-angle glaucoma. Arch
Ophthalmol. 2002;120:701–13.
Editors' note: Drs. Bacharach has
financial interests with Aerie Phar-
maceuticals. Drs. Brubaker, Novack,
and Realini have no financial interests
related to this article.
Contact information
Bacharach: jb@northbayeye.com
Brubaker: jbrubaker@saceye.com
Novack: gary_novack@pharmalogic.com
Realini: hypotony@gmail.com
existing products, creating preser-
vative-free versions, or developing
combination products." The Rho
kinase inhibitors on the horizon
indicate an interest in glaucoma
drug innovations, as does Vesneo
(latanoprostene bunod, Bausch +
Lomb, Bridgewater, N.J., and Nicox,
Sophia Antipolis, France), a nitric
oxide-donating prostaglandin cur-
rently under FDA review, he said.
Dr. Bacharach thinks the FDA
may play a more collaborative role
going forward with the development
of glaucoma therapies. "Although
drug development in glaucoma
has been limited for the past two
decades, I am optimistic for the fu-
ture. The FDA has made it clear that
they want to partner with the R&D
establishment to streamline drug
and device pathways for innovator
companies to follow," he said. EW
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Finding continued from page 53
"
There is more interest in
novel agents than there has
been for quite some time since
prostaglandins came on the scene.
Since then, the majority of research
has been directed toward improving
existing products, creating
preservative-free versions, or
developing combination products.
"
–Jacob Brubaker, MD
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