Eyeworld

D avid Joseph Apple, M.D., died August 18, 2011. He was born on September 14, 1941, in Alton, Ill. He was a graduate of North- western University and the Univer- sity of Illinois College of Medicine. He served his internship and resi- dency in pathology at Louisiana State University. He did postgraduate work in Germany and completed a residency in clinical ophthalmology at the University of Iowa in 1979. He was subsequently an associate professor of ophthalmology at the University of Illinois, Eye and Ear Infirmary. In 1982, he co-founded the Center for Intraocular Research in Salt Lake City with Randall Olson, M.D. He later became profes- sor of ophthalmology and pathology and chairman at the Storm Eye Insti- tute, Medical University of South Carolina, Charleston, where he held the Pawek-Vallotton Chair of Bio- medical Engineering and was the di- rector of the Center for Research in Ocular Therapeutics and Biodevices until 2002. In 2002 he transferred his center to Utah where he became a professor in ophthalmology and pathology and director of the David J. Apple Laboratories for Ophthalmic Device Research, Moran Eye Center, Department of Ophthalmology and Visual Sciences, Salt Lake City. Dr. Apple was an extremely ac- by I. Howard Fine, M.D. A tribute to David J. Apple, M.D. LenSx® Laser Indication: The LenSx® Laser is indicated for use in patients undergoing cataract surgery for removal of the crystalline lens. Intended uses in cataract surgery include anterior capsulotomy, phacofragmentation, and the creation of single plane and multi-plane arc cuts/incisions in the cornea, each of which may be performed either individually or consecutively during the same procedure. Rx Only: United States Federal Law restricts this device to sale and use by or on the order of a physician or licensed eye care practitioner. United States Federal Law restricts the use of this device to practitioners who have been trained in the operation of this device. Restrictions: t 5IJTEFWJDFJTOPUJOUFOEFEGPSVTFJOQFEJBUSJDTVSHFSZ t 1BUJFOUTNVTUCFBCMFUPMJFøBUBOENPUJPOMFTTJOBTVQJOFQPTJUJPO t 1BUJFOUNVTUCFBCMFUPVOEFSTUBOEBOEHJWFBOJOGPSNFEDPOTFOU t 1BUJFOUTNVTUCFBCMFUPUPMFSBUFMPDBMPSUPQJDBMBOFTUIFTJB t 1BUJFOUTXJUIFMFWBUFE*01TIPVMEVTFUPQJDBMTUFSPJETPOMZVOEFS close medical supervision. Contraindications: t $PSOFBMEJTFBTFUIBUQSFDMVEFTBQQMBOBUJPOPGUIFDPSOFBPS transmission of laser light at 1030 nm wavelength t %FTDFNFUPDFMFXJUIJNQFOEJOHDPSOFBMSVQUVSF t $PSOFBMPQBDJUZUIBUXPVMEJOUFSGFSFXJUIUIFMBTFSCFBN t 1SFTFODFPGCMPPEPSPUIFSNBUFSJBMJOUIFBOUFSJPSDIBNCFS t )ZQPUPOZHMBVDPNBPSUIFQSFTFODFPGBDPSOFBMJNQMBOU t 1PPSMZEJMBUJOHQVQJMTVDIUIBUUIFJSJTJTOPUQFSJQIFSBMUPUIF intended diameter for the capsulotomy t $POEJUJPOTXIJDIXPVMEDBVTFJOBEFRVBUFDMFBSBODFCFUXFFO the intended capsulotomy depth and the endothelium (applicable to capsulotomy only) t 1SFWJPVTDPSOFBMJODJTJPOTUIBUNJHIUQSPWJEFBQPUFOUJBMTQBDF into which the gas produced by the procedure can escape t $PSOFBMUIJDLOFTTSFRVJSFNFOUTUIBUBSFCFZPOEUIFSBOHFPG the system t $PSOFBMPQBDJUZUIBUXPVMEJOUFSGFSFXJUIUIFMBTFSCFBN t )ZQPUPOZHMBVDPNBPSUIFQSFTFODFPGBDPSOFBMJNQMBOU t 3FTJEVBMSFDVSSFOUBDUJWFPDVMBSPSFZFMJEEJTFBTFJODMVEJOHBOZ corneal abnormality (for example, recurrent corneal erosion, severe basement membrane disease) t 5IJTEFWJDFJTOPUJOUFOEFEGPSVTFJOQFEJBUSJDTVSHFSZ Warnings: The LenSx® Laser System should only be operated by a physician trained in its use. The LenSx® Laser delivery system employs one sterile disposable LenSx® -BTFS1BUJFOU*OUFSGBDF DPOTJTUJOHPGBOBQQMBOBUJPOMFOTBOETVDUJPOSJOH5IF1BUJFOU*OUFSGBDFJTJOUFOEFEGPSTJOHMFVTF only. The disposables used in conjunction with Alcon® instrument products constitute a complete surgical system. Use of disposables other than those manufactured by Alcon may aect system performance and create potential hazards. The physician should base patient selection criteria on professional experience, published literature, and educational courses. Adult patients should be scheduled to undergo cataract extraction. Precautions: t %POPUVTFDFMMQIPOFTPSQBHFSTPGBOZLJOEJOUIFTBNFSPPNBT the LenSx® Laser. t %JTDBSEVTFE1BUJFOU*OUFSGBDFTBTNFEJDBMXBTUF AEs/Complications: t $BQTVMPUPNZQIBDPGSBHNFOUBUJPOPSDVUPSJODJTJPOEFDFOUSBUJPO t *ODPNQMFUFPSJOUFSSVQUFEDBQTVMPUPNZGSBHNFOUBUJPOPSDPSOFBM incision procedure t $BQTVMBSUFBS t $PSOFBMBCSBTJPOPSEFGFDU t 1BJO t *OGFDUJPO t #MFFEJOH t %BNBHFUPJOUSBPDVMBSTUSVDUVSFT t "OUFSJPSDIBNCFSøVJEMFBLBHFBOUFSJPSDIBNCFSDPMMBQTF t &MFWBUFEQSFTTVSFUPUIFFZF ª/PWBSUJT -49+"% 76645 LSX11502JAD_PI EW.indd 1 9/20/11 2:55 PM complished and highly honored ophthalmologist. His research uti- lized the Miyake-Apple device for microscopic evaluation of the ante- rior segment in enucleated eyes. He contributed an enormous amount of information that dramatically facili- tated and contributed to successful cataract and implant surgery. Among the areas to which he brought evidence-based information were the finishing and polishing of IOLs, IOL designs and materials, fac- tors for delaying posterior capsule opacification, long-term centration of IOLs, measuring the dimensions EW NEWS & OPINION 14 October 2011

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