Eyeworld

FALL 2025

EyeWorld is the official news magazine of the American Society of Cataract & Refractive Surgery.

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z Once you've diagnosed DB, it's time for XDEMVY — the only FDA-approved treatment proven to target and kill Demodex mites. 3 Visit XDEMVYHCP.com INDICATIONS AND USAGE XDEMVY (lotilaner ophthalmic solution) 0.25% is indicated for the treatment of Demodex blepharitis. IMPORTANT SAFETY INFORMATION: WARNINGS AND PRECAUTIONS Risk of Contamination: Do not allow the tip of the dispensing container to contact the eye, surrounding structures, fingers, or any other surface in order to minimize contamination of the solution. Serious damage to the eye and subsequent loss of vision may result from using contaminated solutions. Use with Contact Lenses: XDEMVY contains potassium sorbate, which may discolor soft contact lenses. Contact lenses should be removed prior to instillation of XDEMVY and may be reinserted 15 minutes following its administration. ADVERSE REACTIONS: The most common adverse reaction with XDEMVY was instillation site stinging and burning which was reported in 10% of patients. Other ocular adverse reactions reported in less than 2% of patients were chalazion/hordeolum and punctate keratitis. To report SUSPECTED ADVERSE REACTIONS, contact Tarsus Pharmaceuticals, Inc. at 1-888-421-4002 or the FDA at 1-800-FDA-1088 (www.fda.gov/medwatch). Please see next page for a Brief Summary of the Full Prescribing Information. Available by prescription only. US--2500318 8/25 Evaluate every patient for Demodex blepharitis (DB) OCULAR HEALTH BEGINS WITH THE LIDS References: 1. Trattler W, Karpecki P, Rapoport Y, et al. The prevalence of Demodex blepharitis in US eye care clinic patients as determined by collarettes: a pathognomonic sign. Clin Ophthalmol. 2022;16:1153-1164. 2. Fromstein SR, Harthan JS, Patel J, Opitz DL. Demodex blepharitis: clinical perspectives. Clin Optom (Auckl). 2018;10:57-63. 3. XDEMVY [prescribing information]. Tarsus Pharmaceuticals, Inc; 2023. © 2025 Tarsus Pharmaceuticals, Inc. All rights reserved. Tarsus, XDEMVY, and the associated logos are registered trademarks of Tarsus Pharmaceuticals, Inc. DIAGNOSE DB at the first sign of collarettes 1,2 LOOK down during a slit lamp exam 1 LISTEN to how patients describe their symptoms

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