z
Once you've diagnosed DB, it's time for XDEMVY — the only
FDA-approved treatment proven to target and kill Demodex mites.
3
Visit XDEMVYHCP.com
INDICATIONS AND USAGE
XDEMVY (lotilaner ophthalmic solution) 0.25% is indicated for the treatment of Demodex blepharitis.
IMPORTANT SAFETY INFORMATION:
WARNINGS AND PRECAUTIONS
Risk of Contamination: Do not allow the tip of the dispensing container to contact the eye, surrounding structures,
fingers, or any other surface in order to minimize contamination of the solution. Serious damage to the eye and
subsequent loss of vision may result from using contaminated solutions.
Use with Contact Lenses: XDEMVY contains potassium sorbate, which may discolor soft contact lenses.
Contact lenses should be removed prior to instillation of XDEMVY and may be reinserted 15 minutes following its
administration.
ADVERSE REACTIONS: The most common adverse reaction with XDEMVY was instillation site stinging and burning
which was reported in 10% of patients. Other ocular adverse reactions reported in less than 2% of patients were
chalazion/hordeolum and punctate keratitis.
To report SUSPECTED ADVERSE REACTIONS, contact Tarsus Pharmaceuticals, Inc. at 1-888-421-4002 or the FDA
at 1-800-FDA-1088 (www.fda.gov/medwatch).
Please see next page for a Brief Summary of the Full Prescribing Information.
Available by prescription only.
US--2500318 8/25
Evaluate every patient for
Demodex blepharitis (DB)
OCULAR HEALTH BEGINS WITH THE LIDS
References: 1. Trattler W, Karpecki P, Rapoport Y, et al. The prevalence of Demodex blepharitis in US eye care clinic patients
as determined by collarettes: a pathognomonic sign. Clin Ophthalmol. 2022;16:1153-1164. 2. Fromstein SR, Harthan JS, Patel J,
Opitz DL. Demodex blepharitis: clinical perspectives. Clin Optom (Auckl). 2018;10:57-63. 3. XDEMVY [prescribing information].
Tarsus Pharmaceuticals, Inc; 2023.
© 2025 Tarsus Pharmaceuticals, Inc. All rights reserved. Tarsus, XDEMVY, and the associated
logos are registered trademarks of Tarsus Pharmaceuticals, Inc.
DIAGNOSE DB at
the first sign of
collarettes
1,2
LOOK down
during a
slit lamp exam
1
LISTEN to how
patients
describe their
symptoms