Eyeworld

JUN 2022

EyeWorld is the official news magazine of the American Society of Cataract & Refractive Surgery.

Issue link: https://digital.eyeworld.org/i/1468183

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Year-round control for VKC 1 The first and only topical cyclosporine FDA-approved to treat vernal keratoconjunctivitis (VKC) in children and adults 1 NOW AVAILABLE Reduction in itching and keratitis scores as early as month 1 1 Established 12-month safety profi le with low rates of mild-to-moderate adverse events 1,3 Additional reductions in photophobia, mucous discharge, and tearing observed over 4 months in the pivotal multicenter trial 2 REFERENCES: 1. Verkazia [package insert]. Emeryville, CA: Santen Inc.; 2021. 2. Leonardi A, Doan S, Amrane M, et al; for VEKTIS Study Group. A randomized, controlled trial of cyclosporine A cationic emulsion in pediatric vernal keratoconjunctivitis: the VEKTIS study. Ophthalmology. 2019;126(5):671-681. doi:10.1016/j.ophtha.2018.12.027 3. Bremond-Gignac D, Doan S, Amrane M, et al; for VEKTIS Study Group. Twelve- month results of cyclosporine A cationic emulsion in a randomized study in patients with pediatric vernal keratoconjunctivitis. Am J Ophthalmol. 2020;212:116-126. doi:10.1016/j.ajo.2019.11.020 4. US Department of Health and Human Services. Orange Book: Approved Drug Products With Therapeutic Equivalence Evaluations. 42nd ed. US Government Publishing Offi ce; 2022. Accessed March 16, 2022. https://www.fda.gov/ media/71474/download © 2022 Santen Inc. All rights reserved. VKC-US-220041 INDICATIONS AND USAGE Verkazia ® (cyclosporine ophthalmic emulsion) 0.1% is a calcineurin inhibitor immunosuppressant indicated for the treatment of vernal keratoconjunctivitis in children and adults. IMPORTANT SAFETY INFORMATION WARNINGS AND PRECAUTIONS Potential for eye injury and contamination: To avoid the potential for eye injury and contamination, advise patient not to touch the vial tip to the eye or other surfaces. ADVERSE REACTIONS The most common adverse reactions reported in greater than 5% of patients were eye pain (12%) and eye pruritus (8%), which were usually transitory and occurred during instillation. Harness the highest concentration of cyclosporine available in an eye drop. 1,4 Visit verkazia.com to learn more You are encouraged to report adverse reactions of prescription drugs to Santen at 1-855-7-SANTEN (1-855-772-6836). Or you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. Please see Brief Summary on adjacent page and Full Prescribing Information at verkazia.com.

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