Eyeworld

SEP 2021

EyeWorld is the official news magazine of the American Society of Cataract & Refractive Surgery.

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by Title Contact Name: email Heading Name title Evaluation of intraocular lens position and retinal shape in negative dysphotopsia using high resolution MRI Luc van Vught, BSc, Cornelis Dekker, MSc, Berend Stoel, MSc, PhD, Gregorius Luyten, MD, and Jan-Willem Beenakker, MSc, PhD A case-control study assessed the potential relationship of IOL position and retinal shape in negative dysphotopsia, using high-resolution MRI scans. Thirty-seven patients with negative dysphotopsia were included, along with 26 pseudophakic patients as controls. MRI assessed displace- ment and tilt of in-the-bag IOLs in relation to the pupil and iris and quantified retinal shape. Anterior segment tomography assessed the iris- IOL distance. Overall, the average displacement was less than 0.1 mm and IOL tilt was less than 0.5 degrees in both groups in all directions. The average iris-IOL distance was 1.1 mm in both groups. Retinal shape had large variations, but the authors reported no significant difference between the groups in left-right or anterior-posterior directions. These findings, the authors concluded, show that in-the-bag position and retinal shape are not different between patients with or without negative dysphotopsia. The authors did note that the variation in retinal shape between patients could be important as a factor in the multifactorial origins of negative dysphotopsia. Real-time intraoperative optical coherence tomography imaging of the vitreolenticular interface during pediatric cataract surgery Hedwig Sillen, MD, Jan Van Looveren, MD, Philip Plaeke, MD, Luc Van Os, MD, Marie-José Tassignon, MD Intraoperative OCT was used to visualize the vitreolenticular interface (VLI) during pediatric cataract surgery to determine VLI dysgenesis and surgical difficulties. Fifty-one pediatric patients were included in the research, which included video recording and OCT images. VLI dysgen- esis was considered present when intraoperative OCT images showed partial or total adhesions between the posterior capsule and anterior hyaloid membrane. Twenty-seven patients demonstrated VLI dysgenesis (52.9%); its incidence was higher in children with unilateral cataract (72.4%) and patients with posterior capsule plaque (90%). Surgical challenges included creating the posterior continuous curvilinear capsu- lorhexis (20 patients), defect in the anterior hyaloid membrane (16 pa- tients), and anterior vitrectomy or cutting vitreous strands (10 patients). The authors concluded that intraoperative OCT can be a useful tool to evaluate the VLI and to show VLI dysgenesis during surgery. Endophthalmitis after pediatric cataract surgery in the United States: a report using the Optum insurance claims database Angeline Nguyen, MD, Tawna Roberts, OD, PhD, Won Yeol Ryu, MD, Scott Lambert, MD The incidence of children developing endophthalmitis within 90 days after pediatric cataract surgery, according to a population-based retro- spective cohort study, is more than the rate previously reported by prior studies of patients with similar ages. This study included 58 million charts from Optum's insurance claims database, from which the authors identified patients younger than 13 years old who had bilateral or uni- lateral cataract surgery between 2003–2017. Cataract surgery was per- formed on 789 eyes during this timeframe; 52.6% of the patients were male and the median age was 4 years. Endophthalmitis was diagnosed in 4 eyes (0.51%) with the median time of 6.5 days to diagnosis. Endoph- thalmitis was not significantly associated with factors like age, sex, or primary IOL implantation. Visual outcomes after cataract surgery: topical NSAID prophylaxis compared with prednisolone Neal Shorstein, MD, James Carolan, MD, Liyan Liu, MSc, Stacey Alexeeff, PhD, Laura Amsden, MSW, Lisa Herrinton, PhD The visual outcomes in patients following phacoemulsification com- bined with topical NSAIDS and prednisolone or prednisolone alone were compared in this retrospective cohort study. The study, which used electronic health data from Kaiser Permanente Northern California between June 1, 2010—May 31, 2015, excluding patients with a prior history of macular edema, found that 42% used topical prednisolone alone (n=26,334) and 58% used combined NSAID and prednisolone treatment (n=36,366). The average within-patient change in BCVA from preop to postop measurement was the same amid both groups, but the combination treatment group was more likely to achieve a BCVA of 20/20 or better. Comparison of the upgraded REVO NX with the IOLMaster 700 and the LENSTAR Piotr Kanclerz MD, Kenneth Hoffer, MD, Katarzyna Przewłócka, MSc, Giacomo Savini, MD This study was a prospective evaluation of the REVO NX (Optopol), a spectral-domain optical coherence tomographer with the ability to obtain scans of the anterior and posterior segment that was updated to improve agreement of axial length values with those provided by a validated optical biometer. This research compared the measurements of the updated REVO NX to the IOLMaster 700 (Carl Zeiss Meditec) and the LENSTAR LS-900 (Haag-Streit). The three biometers were used to obtain axial length, anterior chamber depth, corneal thickness, and lens thickness measurements for 63 patients. None of the measurements among the three biometers were clinically significant (less than 0.01 mm differences). Repeated measures analysis of variance showed a statis- tically significant difference in the axial length and corneal thickness measurements. Bland-Altman analysis showed a high level of agreement and strong correlation among the biometers' results. With these results, the authors concluded that the updated REVO NX had a high agreement with validated optical biometers, an improvement over the previous version. Prospective study to compare axial position stability following fellow-eye implantation of two distinct intraocular lens designs Julius Hienert, MD, Nino Hirnschall, MD, Manuel Ruiss, MSc, Marlies Ullrich, MD, Hannah Zwickl, MD, Oliver Findl, MD Axial IOL position and stability of a one-piece C-loop IOL and a four- point haptic IOL were compared in a prospective, randomized, bilateral study. One hundred eyes of 50 patients were implanted with the CT LUCIA 611P (Carl Zeiss Meditec, C-loop design) and the CT ASPHINA 409MP (Carl Zeiss Meditec, four-point haptic design). Anterior cham- ber depth (ACD) was measured at 1 week, 1 month, and 4–6 months postop, in addition to UDVA, CDVA, and subjective refraction assessed 4–6 months postop. Overall, there were significant differences in the IOL design results when it came to postop ACD values, but not in refraction or visual acuity. The overall IOL shift was 0.25±0.16 mm for the four- point haptic and 0.14±0.09 mm for the C-loop. In the journal SEPTEMBER 2021 | EYEWORLD | 39

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