Eyeworld

Quench Dry Eye: New SYSTANE ® HYDRATION PF with HydroBoost Technology * vs. SYSTANE ® ULTR A Lubricant Eye Drops; based on in vitro outcomes using SYSTANE ® HYDR ATION preserved formulation. † These ingredients are also used in SYSTANE ® ULTR A and SYSTANE ® ULTR A PF. ‡ Based on outcomes on Ocular Surface Disease Index (OSDI) in subjects using SYSTANE ® HYDR ATION preserved formulation. References 1. Rangarajan R, Kraybill B, Ogundele A, Ketelson HA. Effects of hyaluronic acid / hydroxypropyl guar artificial tear solution on protection, recovery, and lubricity in models of corneal epithelium. J Ocul Pharmacol Ther. 2015;31:491-497. 2. Alcon data on file, 2014. 3. Davitt WF, Bloomenstein M, Christensen M, Martin AE. Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. J Ocul Pharmacol Ther. 2010;26:347-353. 4. Jones L, Downie LE, Korb D, et al. TFOS DEWS II management and therapy report. Ocul Surf. 2017;15:575-628. 5. Rah MJ. A review of hyaluronan and its ophthalmic applications. Optometry. 2011;82:38-43. 6. Mrukwa-Kominek E, Baranska K, Jadczyk K. First clinical reports on the application of the modern dual-polymer formula in aqueous deficiency dry eye syndrome - Polish observations. Presented at the 20th European Society of Cataract & Refractive Surgery Winter Meeting; February 26–28, 2016; Athens, Greece. This insert was independently produced by Alcon. EyeWorld Magazine had no part in its production. The views expressed here do not necessarily reflect those of the editor, editorial board, or the publisher, and in no way imply endorsement by EyeWorld Magazine or ASCRS. Ocular surgeons know the importance of checking for signs and symptoms of dry eye before surgery, and addressing it as needed. I trust the SYSTANE ® family of artificial tears to provide real dry eye relief for my patients. The SYSTANE ® family includes artificial tear solutions for a wide variety of patient types with varying levels of severity. Alcon's latest addition to the family, SYSTANE ® HYDRATION PF (preservative-free), features HydroBoost Technology, a unique combination of ingredients that helps retain the active lubricants for longer-lasting hydration vs. SYSTANE ULTRA. 1,2* © 2020 Alcon Inc. 3/20 US-SYH-VLC-2000001 S P O N S O R E D CO N T E N T HydroBoost Technology is also added, consisting of the gelling agent HP-GUAR (present in all SYSTANE ® products) 1,3 and sodium hyaluronate, the salt form of hyaluronic acid, a naturally-ocurring substance found in tears that has viscoelastic properties to help retain the active ingredients on the ocular surface and helps the lubricants provide long-lasting hydration. 1,2,4,5 Plus, as its name indicates, SYSTANE ® HYDRATION PF does not contain any preservatives. This formulation makes SYSTANE ® HYDRATION PF with HydroBoost Technology an ideal choice for patients who need long-lasting, preservative-free relief from symptoms of aqueous-deficient dry eye. 6‡ This includes those experiencing frequent symptoms, requiring an artificial tear more than four to six times per day. It may also include patients with other types of dry eye requiring long-lasting symptom relief. SYSTANE ® HYDRATION PF artificial tears are available over the counter in boxes of 30 single-use, sterile vials. I always check for signs and symptoms of dry eye before ocular surgery, and will consider recommending SYSTANE ® HYDRATION PF Preservative-Free Dry Eye Relief to quench the symptoms of dry eye with hydrating relief for my patients. Laura M. Periman, MD Ocular Surface Disease Specialist Director of Dry Eye Services and Clinical Research Seattle, Washington Retention: HP-GUAR HydroBoost Technology Hydration: SODIUM HYALURONATE A unique combination of inactive ingredients which helps retain the dual active lubricants for lasting dry eye symptom relief without preservatives. 6 The new SYSTANE ® HYDRATION PF with HydroBoost Technology has special features that make it an excellent choice for the corneas of dry eye patients who need a preservative-free option. The unique formulation begins with the dual-action lubricants propylene glycol and polyethylene glycol 400, † which work to reduce dry eye symptoms. 3,4

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