JANUARY/FEBRUARY 2020 | EYEWORLD | 39
C
Contact
Donaldson:
KDonaldson@med.miami.edu
Hovanesian:
jhovanesian@harvardeye.com
surgeon places two drops of the liquid into the
activator and mixes it with the white hydrogel
material for about 5 seconds. The mixture is
then applied to the surface of the wound where
it will polymerize.
Dr. Hovanesian noted that wounds need to
be dry before the sealant is applied.
"If it is actively leaking at the time, it is like
trying to put paint on a surface that has a leak
coming through it," Dr. Hovanesian said. "It
doesn't work well."
Lowering the pressure in the eye can re-
duce leaks and provide the 30 seconds it takes
for the sealant to polymerize.
He said the trials compared wounds that
were sutured with those that were closed with
ReSure. They found that the wounds closed
with the sealant were more resistant to external
compression.
"Because of the cost of ReSure, it may not
be for every cataract surgery, but it is a prod-
uct that should be available in every operating
room because a variety of complications can
occur during surgery that make a wound very
hard to seal," Dr. Hovanesian said.
Cases that could benefit from the sealant
include wound burns, pre-existing incisions
(like those from RK), trauma cases, and irregu-
lar corneal incisions. There are certain types of
patients who can benefit from use of a sealant
as well, Dr. Hovanesian said. They include
patients with poorly healing wounds, such as
those with diabetes; those unlikely to take their
drops; those prone to touching their eye; those
prone to complications if wound leak were to
occur (such as patient with IFIS or pseudoex-
foliation); and patients receiving an accommo-
dating IOL where wound seal can help ensure a
good refractive outcome.
ReSure is packaged as two dry components
and a liquid activator in a dropper bottle. The
ReSure Sealant on the eye at the time of surgery. The
sealant has a blue color that disappears in 1 to 2 hours,
and it is also visible with fluorescein staining.
ReSure Sealant is visible on the eye one day after
surgery when stained with fluorescein.
Source (all): John Hovanesian, MD
