Eyeworld

APRIL 2019 | EYEWORLD | 81 C is assessed at 3 years, with a follow-up time of all together 5 years. The study will encompass 11 participating centers in six countries. The results of this study will contribute to a higher patient safety level, as cataract surgeons will be able to better inform myopic patients about their individ- ual risk profile for RD after RLE," he said. RLE is a standardized surgery that can nonetheless bring about serious complications in myopic eyes, such as retinal detachment, cystoid macular edema, and posterior capsule opacifica- tion. According to Dr. Findl, one problem with what we know about pseudophakic retinal de- tachment (PRD) is the difficulty in comparing the data from the literature owing to highly varying study criteria. One study that assessed outcomes from 21 different studies on the subject found the incidence of PRD in myopes is around 2.2%. 6 Evidence suggests patient age as a further influ- ence on the risk of PRD, with younger patients at a higher risk of developing the complication. In the works According to Dr. Findl, retinal detachment is a major issue in RLE, which in a number of studies has been associated with posterior vitreous de- tachment and capsule rupture in eyes with long axial lengths. It is associated with post-surgical pseudophakia and with the mechanical changes within the eye after lens surgery, including the new vitreous composition, which all can contrib- ute to altered forces and differences in dynamic traction. Dr. Findl is the lead investigator in the MYOpic Pseudophakic REtinal Detachment Study (MYOPRED Study), which aims to deter- mine the influence of preoperative and postop- eratively developed PVD on the occurrence of retinal detachment, in a myopic patient collective only. While the association between the occur- rence of PVD and RD is well documented in clinical trials, it has not yet been described for myopic patients, who have a higher risk of devel- oping the complication. The study will involve performing SD-OCT and funduscopy prior to surgery in myopes with an axial length in excess of 25 mm, dividing pa- tients into groups according to PVD levels (com- plete PVD, partial PVD, and no PVD). Patients will be followed after surgery for the incidence of retinal detachment. "We are currently in the recruitment process, having already recruited more than 400 eyes and aiming for 618 with an axial length of 25 mm or longer. The main outcome of retinal detachment Pseudophakic macula-off retinal detachment B-scan ultrasound showing a posterior vitreous detachment before clear lens exchange Source (all): Oliver Findl, MD References 1. Budo C, et al. Multicenter study of the Artisan phakic intraocular lens. J Cataract Refract Surg. 2000;26:1163–71. 2. Jonker SMR, et al. Five- year endothelial cell loss after implantation with Artiflex myopia and Artiflex toric phakic intraoc- ular lenses. Am J Ophthalmol. 2018;194:110–119. 3. Jonker SMR, et al. Long-term endothelial cell loss in patients with Artisan myopia and Artisan toric phakic intraocular lenses. Ophthalmology. 2018;125:486– 494. 4. Morral M, et al. Paired-eye comparison of corneal endothelial cell counts after unilateral iris- claw phakic intraocular lens implantation. J Cataract Refract Surg. 2016;42:117–26. 5. Lim DH, et al. The incidence and risk factors of lens-iris diaphragm retropulsion syndrome during phacoemulsification. Kore- an J Ophthalmol. 2017;31:313– 319. 6. Rosen E. Risk management for rhegmatogenous retinal detach- ment following refractive lens exchange and phakic IOL implan- tation in myopic eyes. J Cataract Refract Surg. 2006;32:697–701. Financial interests Findl: None

• Blank Page
• Blank Page (1)