EW INTERNATIONAL
68
February 2019
"Incisional glaucoma surgery
had a more pronounced effect on
GAT and the 24-hour CLS parame-
ters than both laser trabeculoplasty
and drugs. Surgery > laser = drugs.
Compliance is less of an issue after
surgery," Dr. Cutolo said. "The
CLS can detect changes in patterns
resulting from IOP lowering inter-
ventions beyond daytime GAT IOP,
and this device could potentially be
used to assess treatment efficacy of
IOP lowering interventions in clin-
ical practice and help assess clinical
results. Nocturnal CLS patterns were
most sensitive to all types of inter-
ventions."
According to previously pub-
lished study outcomes by De Moraes
et al. that included 445 treated
glaucoma patients who underwent
24-hour CLS, visual field progres-
sion correlated with CLS recordings.
The number of long peaks during
sleep and the mean peak ratio when
patients were awake were the best
predictors of faster progression.
The combination of CLS parame-
ters provided better measures than
Goldmann applanation IOP parame-
ters (mean, peak, fluctuation) in the
same period.
2
In an unrelated trial, investiga-
tors found the Triggerfish CLS to be
safe and well tolerated for moni-
toring IOP-related patterns and an
option that could expand the IOP
information available to clinicians.
They think the information ob-
tained could have important appli-
cations in identifying high risk pa-
tients and monitoring the response
to treatment interventions.
3
EW
References
1. De Moraes CG, et al. Visual field change and
24-hour IOP-related profile with a contact lens
sensor in treated glaucoma patients. Ophthal-
mology. 2016;123:744–53.
2. De Moraes CG, et al. Association between
24-hour intraocular pressure monitored with
contact lens sensor and visual field progres-
sion in older adults with glaucoma. JAMA
Ophthalmol. 2018;136:779–785.
3. Dunbar GE, et al. The Sensimed Trigger-
fish contact lens sensor: efficacy, safety,
and patient perspectives. Clin Ophthalmol.
2017;11:875–882.
Editors' note: Dr. Cutolo has financial
interests with Sensimed.
Contact information
Cutolo: carloalberto.cutolo@edu.unige.it
24-hour continued from page 66
"
This device could potentially be used to assess
treatment efficacy of IOP lowering interventions in
clinical practice and help assess clinical results.
"
—Carlo Cutolo, MD
