EyeWorld is the official news magazine of the American Society of Cataract & Refractive Surgery.
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EW CATARACT 39 September 2018 routine phaco. Only after lens fragments are removed and with ad- equate corneal visualization would she select a pars plana approach. For planned vitrectomy, such as in the case of repositioning an IOL, for example, she routinely uses a pars plana approach combined with a limbal approach prior to intrascleral, scleral, or iris fixation. Dr. Fram always uses a bimanu- al approach to vitrectomy, keeping her settings on cut/IA. She uses the Centurion Vision System (Alcon, Fort Worth, Texas) at a 4000 cut rate, lowering the bottle height and filling the anterior chamber with viscoelastic or balanced salt solution before removing instruments from the eye to prevent chamber collapse and further vitreous prolapse. "Each surgeon should work within his or her experience and comfort level," Dr. Fram said. If there is still retained lens material, Dr. Hovanesian said he prefers to remove the vitreous that's in the way and then, inserting visco- elastic to keep the chamber full, use manual irrigation/aspiration to remove the remaining cortex. Dr. Weber said if lens fragments present during the vitrectomy, the surgeon should reduce the vitrector to a low cut rate. Using viscoelastic to fill the anterior chamber prior to removing the phaco tip in the event of a pos- terior capsule tear can not only pre- vent further vitreous prolapse, but it can "plug" this hole to allow for safe removal of lens fragments, Dr. Fram said. These fragments should be carefully rotated out of the capsular bag and into the anterior chamber where the surgeon can convert to a small incision extracapsular ap- proach, she said. "Other techniques such as sheets glide placement to keep fragments from falling posteriorly or IOL scaffold have been advocat- ed," Dr. Fram said. "However, these strategies require complex surgical maneuvers that may not be in the comfort zone of all surgeons. A retina specialist can always perform a planned vitrectomy at a later data Dr. Weber said he always uses micronized triamcinolone—a 1:10 dilution with balanced salt solution —in cases where vitreous is present in the anterior chamber, or if there is enough concern that its presence or absence should be verified. "The risk of postoperative com- plications secondary to unaddressed vitreous within the anterior segment requires a surgeon to rule out the presence of vitreous," he explained. Dr. Fram also said she routinely stains the capsule to visualize vitre- ous strands, using preservative-free triamcinolone diluted 1:10 with bal- anced salt solution. She added that she usually performs the bulk of the vitrectomy first, using a bimanual approach, then stains to identify any remaining strands. "There are two reasons to consider the use of preservative-free triamcinolone," Dr. Fram said. "One is diagnostic: improved visualiza- tion of vitreous strands and under- standing of when the vitrectomy is complete; and two is therapeutic: often there is a prolonged surgical time and increased risk of macular edema postoperatively. Intracameral use of diluted steroid may help with postoperative rehabilitation and decrease risk of prolonged postoper- ative inflammation." While Dr. Weber finds the lim- bal approach is often sufficient for anterior vitrectomy, provided the tip of the vitrector is kept posterior to avoid vitreous traction anteriorly, Dr. Hovanesian said he only uses this approach if the vitreous is very minimal. In other cases, Dr. Hovane- sian prefers a pars plana approach, pulling the vitreous back to its more natural space. He said he will put fluid infusion through a limbal incision in the anterior chamber, so fluid is flowing into the eye then out of the eye through the pars plana vitrectomy port. "You want to sweep vitreous into the back of the eye," Dr. Hova- nesian said. Dr. Fram said she prefers to ini- tially use a limbal approach for un- planned anterior vitrectomy during and remove the lens fragments in a safe manner." After the vitrectomy is com- plete and remaining lens material is removed, IOL placement depends on capsular support and the loca- tion of the capsular tear. If there is enough peripheral support (around 210 degrees), Dr. Hovanesian said there is enough to put the optic and haptics fully in the bag. But typical- ly, he, Dr. Weber, and Dr. Fram said, provided there is a round capsulo- tomy, placement of a three-piece IOL in the sulcus with optic capture occurs. Dr. Hovanesian pointed out that one should take into account any power adjustments that might need to be made should the optic be placed in the sulcus. He mentioned the formula on doctor-hill.com, the website of Warren Hill, MD. Gener- ally, the higher power the lens, the more adjustment that needs to be made, Dr. Hovanesian said. In the absence of capsular support, Dr. Fram said an anterior chamber IOL could be used, with measurement for placement includ- ing white-to-white plus 0.5–1 mm. "The surgeon should avoid extending the clear corneal incision and move superiorly for a fresh scleral tunnel measuring 6 mm as this will reduce iris prolapse and irregular corneal astigmatism," Dr. Fram explained. "Acetylcholine chloride should be placed, and a mid-peripheral SPI can be made with the vitrector (100 cut rate and 700 vacuum). The ACIOL can then be placed carefully using the help of a sheets glide. Alternatively, one can perform intrascleral or scleral suture fixation, depending on surgeon experience." Dr. Weber performs a dilated exam of the posterior segment with- in the early postoperative course, but his medication instructions re- main the same as an uncomplicated case. Dr. Hovanesian said he treats the patient longer with steroids and NSAIDs. Dr. Fram said she instructs patients to call if they experience extreme pain or discomfort postop- eratively, as it could indicate high intraocular pressure. The physicians said they are forthright with the patient after surgery about what happened. Preoperatively, Dr. Hovanesian discusses the odds of complica- tions with his patients. There is a 1 in 1,000 chance that a major complication could occur and a 1 in 100 chance for a minor but not vision-threatening complication. The situations meriting an anterior vitrectomy fall into the latter camp. "I usually refer back to our conversation before surgery," Dr. Hovanesian said, adding that he explains that while he tried to keep the lens capsule as intact as possi- ble, a complication occurred that required additional steps to the cataract surgery. He tells patients, "I think you're going to do well, but it may take longer for you to achieve that final vision than a normal person. I wish that it didn't happen, but I'm happy with the way things turned out." As a final pearl of advice, Dr. Weber recommended young surgeons get to know the different vitrectomy settings and seek out videos of the various vitrectomy techniques. Dr. Fram pointed out that there are tools for practicing anterior vitrectomy with SimulEYE (Westlake Village, California). All in all, Dr. Hovanesian said, what makes a good surgeon is how the surgeon handles the vitreous loss. "The measure of a skilled surgeon is someone who keeps their head about them and diligently pursues getting all of the vitreous, getting all the lens material, get- ting a round pupil, and getting the patient a good result from surgery even when things go poorly," he said. EW Editors' note: The physicians have no financial interests related to their comments. Contact information Fram: nicfram@yahoo.com Hovanesian: drhovanesian@harvardeye.com Weber: charles.weber@gmail.com